QRS Vector Magnitude as Predictor of Ventricular Arrhythmia in Patients With Brugada Syndrome

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Vagally mediated ventricular arrhythmia in Brugada syndrome

Case report A 44-year-old man was admitted to the hospital after 2 episodes of syncope. Upon waking up at midnight, the patient proceeded to urinate, went back to his bed, and passed out. His wife noticed that he was not responding and started cardiopulmonary resuscitation. After about 2 minutes, the patient started to respond. An emergency medical services team was called, but before their arr...

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Meta-analysis of Fragmented QRS as an Electrocardiographic Predictor for Arrhythmic Events in Patients with Brugada Syndrome

Fragmented QRS (fQRS) is an electrocardiographic marker related to ventricular fibrillation (VF) and sudden cardiac death (SCD) in various clinical settings. Current data regarding the prognostic significance of fQRS in Brugada syndrome (BrS) are contradictory. This meta-analysis aimed to evaluate the presence of fQRS as a risk stratification tool in BrS. Electronic databases (PubMed, EMBASE, a...

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Fragmented QRS as a marker of conduction abnormality and a predictor of prognosis of Brugada syndrome.

BACKGROUND Conduction abnormalities serve as a substrate for ventricular fibrillation (VF) in patients with Brugada syndrome (BS). Signal-averaged electrograms can detect late potentials, but the significance of conduction abnormalities within the QRS complex is still unknown. The latter can present as multiple spikes within the QRS complex (fragmented QRS [f-QRS]). We hypothesized that f-QRS c...

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Low-dose isoproterenol for repetitive ventricular arrhythmia in patients with Brugada syndrome.

AIMS Arrhythmic storm or repetitive ventricular arrhythmia (VA) has been occasionally observed in Brugada syndrome (BS). A beta-adrenergic stimulator [isoproterenol (ISP)] has been reported to suppress this arrhythmic storm in sporadic cases. Accordingly, we investigated the antiarrhythmic effects of ISP infusion in consecutive BS patients with arrhythmic storm or repetitive VA. METHODS AND R...

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Ventricular arrhythmia induced by sodium channel blocker in patients with Brugada syndrome.

OBJECTIVES We administered pilsicainide chloride, a class Ic pure sodium channel blocker, to patients with Brugada syndrome (BS) and evaluated the occurrence of ventricular arrhythmia (VA) and T-wave alternans (TWA). BACKGROUND Ventricular arrhythmia and TWA are sometimes induced by a sodium channel blocker challenge test in BS patients, but the significance of the induced VA and TWA is not k...

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ژورنال

عنوان ژورنال: The American Journal of Cardiology

سال: 2019

ISSN: 0002-9149

DOI: 10.1016/j.amjcard.2019.03.018